Professor Moganavelli Singh

Singh 
 

Professor Singh's research is in the area of non-viral gene and drug delivery systems. This involves the design, synthesis, characterization and biological evaluation of potential nanoparticles such as lipids, polymers, and inorganic nanoparticles (gold, silver, iron oxide, silica). Studies include intensive screening of anticancer activities of novel drug nanocomplexes in vitro.
     
Position:   Associate Professor
Qualifications:   PhD (Biochemistry)
MSc
     
Discipline:   Biochemistry
Campus:   Westville
Telephone:   031 260 7170
 Email:   singhm1@ukzn.ac.za
     
 Research Areas:  

Nanotherapeutics: Gene therapy, Drug Delivery, Anticancer studies, Gene Silencing

 Recent Publications:  
. Maney,V. and Singh,M (2017). An in vitro assessment of novel Chitosan/ Bimetallic PtAu nanocomposites as delivery vehicles for Doxorubicin’. Nanomedicine. https://doi.org/10.2217/nnm-2017-0228. Impact factor = 4.727
2. Maiyo F and Singh M (2017). "Selenium Nanoparticles: Potential in Cancer Gene and Drug Delivery". Nanomedicine. 12 (9): 1075-1089. DOI:10.2217/nnm-2017-0024. Impact factor = 4.727
3. Lazarus,G. and  Singh,M.(2016)  “Cationic modified gold nanoparticles show enhanced gene delivery in vitro”  Nanotechnology Reviews. 5(5): 425–434,  ISSN (Online) 2191-9097, ISSN (Print) 2191-9089, DOI: 10.1515/ntrev-2016-0003, June 2016.Impact factor = 2.044 
4. Lazarus,G. and Singh,M. (2016). “In vitro cytotoxic activity and transfection efficiency of polyethyleneimine functionalized gold nanoparticles”.Colloids and Surfaces B: Biointerfaces. 145: 906–911.  DOI: http://dx.doi.org/doi:10.1016/j.colsurfb.2016.05.072. Impact factor = 4.287
5. Maiyo ,F., Moodley, R. and Singh, M.  (2016).  “Cytotoxicity, antioxidant and apoptosis studies of Quercetin-3-O-glucoside and 4-(β-D-Glucopyranosyl-1→4-α-L-Rhamnopyranosyloxy)-benzyl isothiocyanate from Moringa oleifera”. Anti-cancer agents in Medicinal Chemistry. 16, (5) 648 – 656. Impact factor = 2.722.  DOI: 10.2174/1871520615666151002110424

Maney,V. and Singh,M (2017). An in vitro assessment of novel Chitosan/ Bimetallic PtAu nanocomposites as delivery vehicles for Doxorubicin’. Nanomedicine. https://doi.org/10.2217/nnm-2017-0228. Impact factor = 4.727


Maiyo F and Singh M (2017). "Selenium Nanoparticles: Potential in Cancer Gene and Drug Delivery". Nanomedicine. 12 (9): 1075-1089. DOI:10.2217/nnm-2017-0024. Impact factor = 4.727


Lazarus,G. and  Singh,M.(2016)  “Cationic modified gold nanoparticles show enhanced gene delivery in vitro”  Nanotechnology Reviews. 5(5): 425–434,  ISSN (Online) 2191-9097, ISSN (Print) 2191-9089, DOI: 10.1515/ntrev-2016-0003, June 2016.Impact factor = 2.044


Lazarus,G. and Singh,M. (2016). “In vitro cytotoxic activity and transfection efficiency of polyethyleneimine functionalized gold nanoparticles”.Colloids and Surfaces B: Biointerfaces. 145: 906–911.  DOI: http://dx.doi.org/doi:10.1016/j.colsurfb.2016.05.072. Impact factor = 4.287


Maiyo ,F., Moodley, R. and Singh, M.  (2016).  “Cytotoxicity, antioxidant and apoptosis studies of Quercetin-3-O-glucoside and 4-(β-D-Glucopyranosyl-1→4-α-L-Rhamnopyranosyloxy)-benzyl isothiocyanate from Moringa oleifera”. Anti-cancer agents in Medicinal Chemistry. 16, (5) 648 – 656. Impact factor = 2.722.  DOI: 10.2174/1871520615666151002110424


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